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News & Press: Sep 2011

Mahaveer Golechha takes lead in Alzheimer's Drug Discovery Research

Thursday, September 22, 2011   (0 Comments)
Posted by: BITSAA Newsletter
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Mahaveer Golechha is the only Indian to be awarded a scholarship for outstanding research on Alzheimer's disease by the Alzheimer's Drug Discovery Foundation, USA. He is an alumnus of BITS Pilani and is currently a researcher at AIIMS. He was one of the 25 recipients of this award at the 5th drug discovery conference on neurodegeneration held in California, USA. Golechha has been involved in the research of neuroprotective role of natural antioxidants in neurodegenerative disorders since 2006.

"I was interested in neurodegenerative disorders because it's a very neglected field. While there are hundreds of drugs and several treatments for cardiovascular diseases, there are only handful drugs for diseases such as Alzeimer's and hardly any treatment," he said.

Alzheimer's disease is a neurodegenerative disorder that generally affects the elderly population and is characterised by progressive degeneration and loss of neurons in the brain. India has over 3.7 million people suffering from this disease and all the four drugs approved for Alzheimer's disease have several side effects, which is one reason as to why Golechha developed a keen interest in studying the neuroprotective properties of natural antioxidants.

"Naringin has an advantage over existing drugs because its source is natural," he said.

In his study, submitted to the Alzheimer's Drug Discovery Foundation, Mahaveer had evaluated the neuroprotective mechanism and properties of 'Naringin', a bioflavonoid found in grape fruits and citrus fruits. He found that it possessed antioxidant, antiinflammatory, beta amyloid inhibitory and acetylchoniesterase inhibitory activities.

Congratulations and all the very best for further research.

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